Restylane® Refyne is designed with XpresHAn Technology™ to help soften laugh lines (nasolabial folds and marionette lines). This can help you restore a more natural look to your face while maintaining your facial expressions.1-4 So, you always look like you. Talk to your specialist and see for yourself why it’s worth it.
What is Restylane Refyne for?
As you age, your facial skin begins to lose its elasticity and volume. As a result, your “laugh lines”, the creases that run from the sides of your nose toward the corners of your mouth, become more pronounced. Restylane Refyne injectable gel is designed to temporarily help counter this by smoothing out these wrinkles and folds and restoring a natural, soft look to your face. Restylane Refyne has been shown to maintain this effect for up to 12 months.
How is Restylane Refyne used?
Restylane Refyne is injected into the facial skin through a small needle to smooth facial wrinkles and folds (laugh lines), resulting in a more youthful appearance of the skin. For most patients, the procedure only takes 15 – 30 minutes
How was Restylane Refyne Studied?
Restylane Refyne was tested to ensure that it worked properly (effective) and was safe to use, in 170 patients before it was approved for use in all patients. These patients included 160 women, 10 men, and were from various ethnic groups with multiple skin tones (pale to dark skin). Each of these patients expressed desire to improve the appearance of their facial wrinkles and folds (laugh lines).
What will Restylane Refyne do for me?
Restylane Refyne temporarily reduces signs of aging on your face by smoothing the wrinkles and folds that form around your nose and extend down to the corners of your mouth (laugh lines). This natural, smooth look should last for up to 12 months.
What side effects were seen in the clinical study?
In the study of Restylane Refyne, most patients reported the following side effects at the site where they received the injection:
Most patients said their side effects were mild, short-lived and did not require them to call their doctor. These patients said that their side effects disappeared within 1-2 weeks.
|Treatment Type||Filler, Injectables|
|Treatment Problem or Condition||Facial Volume Loss, Fine Lines, Sagging/Loose Skin, Thin Lips, Wrinkles|
|Size||1 cc syringe|
Restylane® Refyne is for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21.
- Restylane Refyne is contraindicated for patients with severe allergies manifested by a history of anaphylaxis or history or presence of multiple severe allergies.
- Restylane Refyne may contain trace amounts of gram-positive bacterial proteins and is contraindicated for patients with a history of allergies to such material.
- Restylane Refyne contains lidocaine and is contraindicated for patients with a history of allergies to such material.
Restylane® Refyne is a sterile, biodegradable, viscoelastic, non-pyrogenic, clear, colorless, and homogeneous soft hyaluronic acid gel with a moderate lifting capacity. The product has a sodium hyaluronate concentration of 20 mg/mL in phosphate buffered saline at pH 7 and contains 3 mg/mL lidocaine hydrochloride.